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Takeda-6d

Product Specifications

CAS Number

1125632-93-0

Target

Raf, VEGFR, PERK

Related Pathways

MAPK, Apoptosis, Tyrosine Kinase/Adaptors, Angiogenesis

Purity

0.9841

Bioactivity

Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.

Smiles

Fc1ccc(Oc2ccc3nc(NC(=O)C4CC4)sc3n2)cc1NC(=O)c1cccc(c1Cl)C1(CC1)C#N

Molecular Formula

C27H19ClFN5O3S

Molecular Weight

547.99

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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