Quinacrine Dihydrochloride Dihydrate
Product Specifications
CAS Number
6151-30-0
Target
Parasite, Autophagy, Apoptosis, p53, Antibiotic, Topoisomerase, Wnt/beta-catenin
Related Pathways
Autophagy, Apoptosis, Stem Cells, DNA Damage/DNA Repair, Cytoskeletal Signaling, Microbiology/Virology
Bioactivity
Quinacrine Dihydrochloride Dihydrate is an orally available antimalarial agent capable of crossing the blood-brain barrier. It exhibits anticancer activity by inhibiting WNT/TCF and topoisomerase, inducing autophagy and apoptosis, and activating p53. Quinacrine is an acridine dye derivative used for DNA and RNA staining in fixed cells (Ex/Em=436/525 nm) .
Smiles
ClC(C=CC1=C2NC(CCCN(CC)CC)C)=CC1=NC3=C2C=C(OC)C=C3.Cl.O.Cl.O
Molecular Formula
C23H36Cl3N3O3
Molecular Weight
508.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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