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Alisertib

Product Specifications

CAS Number

1028486-01-2

Target

Apoptosis, Autophagy, Aurora Kinase

Related Pathways

Apoptosis, Autophagy, Cell Cycle/Checkpoint, Chromatin/Epigenetic

Purity

>99.99%

Bioactivity

Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM) . The selectivity of Alisertib (MLN 8237) is >200-fold higher for Aurora A than Aurora B.

Smiles

COc1cc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2OC)ccc1C(O)=O

Molecular Formula

C27H20ClFN4O4

Molecular Weight

518.92

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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