Alisertib
Product Specifications
CAS Number
1028486-01-2
Target
Apoptosis, Autophagy, Aurora Kinase
Related Pathways
Apoptosis, Autophagy, Cell Cycle/Checkpoint, Chromatin/Epigenetic
Purity
>99.99%
Bioactivity
Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM) . The selectivity of Alisertib (MLN 8237) is >200-fold higher for Aurora A than Aurora B.
Smiles
COc1cc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2OC)ccc1C(O)=O
Molecular Formula
C27H20ClFN4O4
Molecular Weight
518.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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