PNU-282987 S enantiomer hydrochloride
Product Specifications
CAS Number
128311-08-0
Target
5-HT Receptor, AChR, Others
Related Pathways
GPCR/G Protein, Others, Neuroscience
Bioactivity
(S) -PNU-282987 is the absolute stereochemistry form of PNU-282987. PNU 282987, a potent agonist of α7-containing neuronal nicotinic acetylcholine receptors (nAChRs) with Ki of 26 nM for the rat receptor, has negligible activity against α1β1γδ and α3β4 nAChRs as well as a panel of monoamine, glutamate, muscarinic, and GABA receptors, except 5-HT3 with Ki of 930 nM.
Smiles
Cl.Clc1ccc(cc1)C(=O)N[C@@H]1CN2CCC1CC2 |THB:10:11:15.14:18.17|
Molecular Formula
C14H18Cl2N2O
Molecular Weight
301.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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