Dactolisib
Product Specifications
CAS Number
915019-65-7
Target
Autophagy, mTOR, ATM/ATR, PI3K
Related Pathways
Autophagy, DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling
Purity
0.9985
Bioactivity
Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR, with IC50 values of 4 nM for p110α, 5 nM for p110γ, 7 nM for p110δ, 75 nM for p110β, and 20.7 nM for mTOR.
Smiles
O=C1N(C=2C=3C(N=CC2N1C)=CC=C(C3)C4=CC5=C(N=C4)C=CC=C5)C6=CC=C(C(C#N)(C)C)C=C6
Molecular Formula
C30H23N5O
Molecular Weight
469.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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