Dactolisib

Product Specifications

CAS Number

915019-65-7

Target

Autophagy|||mTOR|||ATM/ATR|||PI3K

Related Pathways

Autophagy|||DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling

Purity

0.9985

Bioactivity

Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR, with IC50 values of 4 nM for p110?, 5 nM for p110?, 7 nM for p110?, 75 nM for p110?, and 20.7 nM for mTOR.

Smiles

O=C1N(C=2C=3C(N=CC2N1C)=CC=C(C3)C4=CC5=C(N=C4)C=CC=C5)C6=CC=C(C(C#N)(C)C)C=C6

Molecular Formula

C30H23N5O

Molecular Weight

469.54

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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