Ensartinib hydrochloride
Product Specifications
CAS Number
2137030-98-7
Target
ALK, c-Met/HGFR, Trk receptor
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9929
Bioactivity
Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both wild-type ALK and ALK variants (C1156Y, F1174, G1202R, L1196M, S1206R, and T1151 mutants) with in vitro IC50s of <4 nM.
Smiles
Cl.Cl.C[C@@H](Oc1cc(nnc1N)C(=O)Nc1ccc(cc1)C(=O)N1C[C@H](C)N[C@H](C)C1)c1c(Cl)ccc(F)c1Cl
Molecular Formula
C26H29Cl4FN6O3
Molecular Weight
634.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7169250 Inquire
Rabbit anti-Escherichia coli O9:H4 (strain HS) RLMG Polyclonal Antibody
Sign In for Pricing
View Details 
NBP1-68889 100 µL
Rabbit Polyclonal Carbonic Anhydrase VA/CA5A Antibody
Sign In for Pricing
View Details ABP-S-021124 5 Plates
Rat IL-1 alpha Matched Antibody Pair Set [ABP-S-021124]
Sign In for Pricing
View Details K6739306 1.0 µg DNA
Aox1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
Sign In for Pricing
View Details