Ensartinib hydrochloride
Product Specifications
CAS Number
2137030-98-7
Target
ALK|||c-Met/HGFR|||Trk receptor
Related Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors
Purity
0.9929
Bioactivity
Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both wild-type ALK and ALK variants (C1156Y, F1174, G1202R, L1196M, S1206R, and T1151 mutants) with in vitro IC50s of <4 nM.
Smiles
Cl.Cl.C[C@@H](Oc1cc(nnc1N)C(=O)Nc1ccc(cc1)C(=O)N1C[C@H](C)N[C@H](C)C1)c1c(Cl)ccc(F)c1Cl
Molecular Formula
C26H29Cl4FN6O3
Molecular Weight
634.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
R1399TR 1 mg
Human IgA + IgG + IgM (adsorbed F(ab)2 Fragment) Goat Polyclonal Antibody
Ask
View Details MBS1213833-01 0.02 mg (E-Coli)
Recombinant Bacillus anthracis Chaperone protein DnaJ (dnaJ)
Ask
View Details 
MBS1213833-02 0.02 mg (Yeast)
Recombinant Bacillus anthracis Chaperone protein DnaJ (dnaJ)
Ask
View Details MBS1213833-03 0.1 mg (E-Coli)
Recombinant Bacillus anthracis Chaperone protein DnaJ (dnaJ)
Ask
View Details MBS1213833-04 0.1 mg (Yeast)
Recombinant Bacillus anthracis Chaperone protein DnaJ (dnaJ)
Ask
View Details MBS1213833-05 0.02 mg (Baculovirus)
Recombinant Bacillus anthracis Chaperone protein DnaJ (dnaJ)
Ask
View Details