BMS-P5 free base
Product Specifications
CAS Number
1550371-22-6
Target
PAD
Related Pathways
Chromatin/Epigenetic
Purity
0.9996
Bioactivity
BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor that blocks the formation of Neutrophil Extracellular Traps and delays the progression of multiple myeloma. Administration of BMS-P5 to multiple myeloma-bearing mice delays symptom onset and disease progression. Targeting PAD4 may be beneficial for treating multiple myeloma.
Smiles
COc1cc(cc2nc(-c3cc4cccnc4n3CC3CC3)n(C)c12)C(=O)N1C[C@H](N)CC[C@@H]1C
Molecular Formula
C27H32N6O2
Molecular Weight
472.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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