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BMS-P5 free base

Product Specifications

CAS Number

1550371-22-6

Target

PAD

Related Pathways

Chromatin/Epigenetic

Purity

0.9996

Bioactivity

BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor that blocks the formation of Neutrophil Extracellular Traps and delays the progression of multiple myeloma. Administration of BMS-P5 to multiple myeloma-bearing mice delays symptom onset and disease progression. Targeting PAD4 may be beneficial for treating multiple myeloma.

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COc1cc(cc2nc(-c3cc4cccnc4n3CC3CC3)n(C)c12)C(=O)N1C[C@H](N)CC[C@@H]1C

Molecular Formula

C27H32N6O2

Molecular Weight

472.58

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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