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Bis (maltolato) oxovanadium (IV)

Product Specifications

CAS Number

38213-69-3

Target

Phosphatase

Related Pathways

Metabolism

Purity

0.9992

Bioactivity

Bis (maltolato) oxovanadium (IV) (BMOV) is a potent, reversible, competitive, and orally active pan-PTP (protein tyrosine phosphatases) inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent insulin sensitizer and has been shown to improve cardiac dysfunctions in diabetic models. BMOV inhibits HCPTPA, PTP1B, HPTP?, and SHP2 with IC50s of 126 nM, 109 nM, 26 nM, and 201 nM, respectively [1][2].

Smiles

O=[V+2]12([O-]C=3C(=O1)C=COC3C)[O-]C=4C(=O2)C=COC4C

Molecular Formula

C12H10O7V

Molecular Weight

317.15

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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