Aminopurvalanol A
Product Specifications
CAS Number
220792-57-4
Target
Apoptosis, CDK
Related Pathways
Cell Cycle/Checkpoint, Apoptosis
Purity
0.9973
Bioactivity
Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1, Cyclin E/cdk2, and P35/cdk5 with IC50 of 33 nM, 33 nM, 28 nM and 20 nM, respectively.
Smiles
CC(C)[C@H](CO)Nc1nc(Nc2cc(N)cc(Cl)c2)c2ncn(C(C)C)c2n1
Molecular Formula
C19H26ClN7O
Molecular Weight
403.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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