Aminopurvalanol A

Product Specifications

CAS Number

220792-57-4

Target

Apoptosis, CDK

Related Pathways

Cell Cycle/Checkpoint, Apoptosis

Purity

0.9973

Bioactivity

Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1, Cyclin E/cdk2, and P35/cdk5 with IC50 of 33 nM, 33 nM, 28 nM and 20 nM, respectively.

Smiles

CC(C)[C@H](CO)Nc1nc(Nc2cc(N)cc(Cl)c2)c2ncn(C(C)C)c2n1

Molecular Formula

C19H26ClN7O

Molecular Weight

403.91

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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