(S) -AMG-510
Product Specifications
CAS Number
2252403-56-6
Target
Kras, Ras, p38 MAPK
Related Pathways
MAPK, GPCR/G Protein
Purity
0.9976
Bioactivity
(S) -AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C through covalent interaction with mutant cysteine, thereby promoting clinical efficacy in KRASG12C tumors.
Smiles
O=C1N(C=2C(C(=N1)N3[C@@H](C)CN(C(C=C)=O)CC3)=CC(F)=C(N2)C4=C(F)C=CC=C4O)C5=C(C(C)C)N=CC=C5C
Molecular Formula
C30H30F2N6O3
Molecular Weight
560.594
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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