(S) -AMG-510

Product Specifications

CAS Number

2252403-56-6

Target

Kras|||Ras|||p38 MAPK

Related Pathways

MAPK|||GPCR/G Protein

Purity

0.9976

Bioactivity

(S) -AMG-510 is the S-type compound of AMG-510 (Sotorasib), which effectively and selectively inhibits KRASG12C through covalent interaction with mutant cysteine, thereby promoting clinical efficacy in KRASG12C tumors.

Smiles

O=C1N(C=2C(C(=N1)N3[C@@H](C)CN(C(C=C)=O)CC3)=CC(F)=C(N2)C4=C(F)C=CC=C4O)C5=C(C(C)C)N=CC=C5C

Molecular Formula

C30H30F2N6O3

Molecular Weight

560.594

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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