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Amodiaquine hydrochloride

Product Specifications

CAS Number

69-44-3

Target

Others|||NR4A|||Parasite|||Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic|||Endocrinology/Hormones|||Others|||Microbiology/Virology

Bioactivity

Amodiaquine dihydrochloride (Amodiaquin dihydrochloride), a member of the 4-aminoquinoline class, is an antimalarial agent that also acts as a potent oral histamine N-methyltransferase inhibitor with a K i value of 18.6 nM. Additionally, it functions as a Nurr1 agonist, targeting the Nurr1-LBD (ligand binding domain) with an EC 50 of approximately 20 ?M, demonstrating anti-inflammatory effects [1] [2] [3] [4] [5].

Smiles

CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O.Cl.Cl

Molecular Formula

C20H24Cl3N3O

Molecular Weight

428.78

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Curated Selection

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