YS-121
Product Specifications
CAS Number
916482-17-2
Target
Others, PGE Synthase, Lipoxygenase
Related Pathways
Metabolism, Immunology/Inflammation, Others
Bioactivity
YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1; IC50=3.4 μM) and 5-lipoxygenase (5-LOX; IC50=6.5 μM) . YS121 dose-dependently reduces the production of PGE2 with EC50=12 μM in IL-1β-stimulated A549 cells [1].
Smiles
N(C1=NC(SC(CCCCCC)C(O)=O)=NC(Cl)=C1)C2=C(C)C(C)=CC=C2
Molecular Formula
C20H26ClN3O2S
Molecular Weight
407.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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