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PD 166326

Product Specifications

CAS Number

185039-91-2

Target

BCRP, Others, Src

Related Pathways

Membrane transporter/Ion channel, Others, Angiogenesis, Tyrosine Kinase/Adaptors

Bioactivity

PD166326, a pyridopyrimidine-type inhibitor of receptor tyrosine kinases, demonstrates antileukemic activity with IC50 values of 6 nM for Src and 8 nM for Abl. [1] [2].

Smiles

O=C1C(=CC=2C(N1C)=NC(NC3=CC(CO)=CC=C3)=NC2)C4=C(Cl)C=CC=C4Cl

Molecular Formula

C21H16Cl2N4O2

Molecular Weight

427.28

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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