PD 166326
Product Specifications
CAS Number
185039-91-2
Target
BCRP, Others, Src
Related Pathways
Membrane transporter/Ion channel, Others, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
PD166326, a pyridopyrimidine-type inhibitor of receptor tyrosine kinases, demonstrates antileukemic activity with IC50 values of 6 nM for Src and 8 nM for Abl. [1] [2].
Smiles
O=C1C(=CC=2C(N1C)=NC(NC3=CC(CO)=CC=C3)=NC2)C4=C(Cl)C=CC=C4Cl
Molecular Formula
C21H16Cl2N4O2
Molecular Weight
427.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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