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Org 25543 hydrochloride

Product Specifications

CAS Number

495076-64-7

Target

GlyT

Related Pathways

Neuroscience

Purity

0.9934

Bioactivity

Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2) . Displays no activity at GlyT1 or 56 other common biological targets (≥ 100 μM), in a glycine uptake assay in CHO cells.

Smiles

Cl.COc1cc(cc(OC)c1OCc1ccccc1)C(=O)NCC1(CCCC1)N(C)C

Molecular Formula

C24H33ClN2O4

Molecular Weight

448.983

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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