ONO-8711
Product Specifications
CAS Number
216158-34-8
Target
Prostaglandin Receptor, Others
Related Pathways
Immunology/Inflammation, Others, GPCR/G Protein
Bioactivity
ONO-8711 is a potent and selective competitive antagonist of the EP1 receptor, with Ki values of 0.6 nM for human EP1 and 1.7 nM for mouse EP1. It effectively reduces tumor incidence and multiplicity in mouse models of colon, breast, and oral cancer [1].
Smiles
C(NS(=O)(=O)C1=C(C)C=C(Cl)C=C1)[C@@H]2[C@@H](/C=C\CCCC(O)=O)C3CCC2CC3
Molecular Formula
C22H30ClNO4S
Molecular Weight
440
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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