ML-291
Product Specifications
CAS Number
1523437-16-2
Target
Others, PERK, Apoptosis
Related Pathways
Others, Apoptosis
Bioactivity
ML291 is a sufonamidebenzamide compound that induces the unfolded protein response (UPR) and overwhelms the adaptive capacity of UPR, resulting in apoptosis in various solid cancer models. It activates the PERK/eIF2a/CHOP apoptotic pathway of UPR and reduces leukemic cell burden [1].
Smiles
[O-][N+](=O)c1ccc(o1)C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCC(Cl)CC1
Molecular Formula
C16H16ClN3O6S
Molecular Weight
413.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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