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HPI 1

Product Specifications

CAS Number

599150-20-6

Target

Hedgehog/Smoothened

Related Pathways

GPCR/G Protein, Stem Cells

Purity

0.976

Bioactivity

HPI 1 is a hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh) -, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4, and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced activation) .

Smiles

COCCOC(=O)C1C(C2=CC(O)=CC=C2)C2=C(CC(CC2=O)C2=C(OC)C=CC=C2)N=C1C

Molecular Formula

C27H29NO6

Molecular Weight

463.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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