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A 987306

Product Specifications

CAS Number

1082954-71-9

Target

Histamine Receptor, Others

Related Pathways

GPCR/G Protein, Others, Immunology/Inflammation, Neuroscience

Bioactivity

A-987306 is a potent and orally bioavailable histamine H4 antagonist with Kis of 3.4 nM and 5.8 nM for rat H4 and human H4, respectively. A-987306 exhibits anti-inflammatory activity in a mouse peritonitis model [1].

Smiles

NC=1N=C2C=3[C@]4([C@@](OC3CCC2=C(N1)N5CCNCC5)(CCCC4)[H])[H]

Molecular Formula

C18H25N5O

Molecular Weight

327.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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