(±) -J 113397
Product Specifications
CAS Number
217461-40-0
Target
Others, Opioid Receptor
Related Pathways
GPCR/G Protein, Endocrinology/Hormones, Neuroscience, Others
Bioactivity
(±) -J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K (i) : cloned human ORL1=1.8 nM) . J-113397 inhibited nociceptin/orphanin FQ-stimulated GTPγS binding to CHO cells expressing ORL1 with an IC50 value of 5.3 nM. J-113397 can be used for researching the physiological roles of nociceptin/orphanin FQ [1].
Smiles
O=C1N(C=2C(N1CC)=CC=CC2)[C@@H]3[C@@H](CO)CN(CC4CCCCCCC4)CC3
Molecular Formula
C24H37N3O2
Molecular Weight
399.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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