Vacuolin-1
Product Specifications
CAS Number
351986-85-1
Target
Autophagy, PI3K
Related Pathways
Autophagy, PI3K/Akt/mTOR signaling
Purity
0.9945
Bioactivity
Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation
Smiles
Ic1cccc(\C=N\Nc2nc(nc(n2)N2CCOCC2)N(c2ccccc2)c2ccccc2)c1
Molecular Formula
C26H24IN7O
Molecular Weight
577.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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