UMB-32
Product Specifications
CAS Number
1635437-39-6
Target
Epigenetic Reader Domain, Others
Related Pathways
Chromatin/Epigenetic, Others
Bioactivity
UMB-32 is a potent and selective BRD4 inhibitor, demonstrating an affinity for BRD4 with a dissociation constant (K d) of 550 nM and an inhibitory concentration 50 (IC 50) of 637 nM. Moreover, UMB-32 exhibits effectiveness against TAF1, a bromodomain-containing transcription factor [1].
Smiles
N(C(C)(C)C)C1=C(N=C2N1C=CN=C2)C3=CC=C(C=C3)C=4C(C)=NOC4C
Molecular Formula
C21H23N5O
Molecular Weight
361.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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