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TC-SP 14

Product Specifications

CAS Number

1257093-40-5

Target

Others, LPL Receptor

Related Pathways

GPCR/G Protein, Others

Bioactivity

TC-SP 14, also known as compound 14, is a highly active and potent S1P1 agonist with oral bioavailability. It exhibits an EC50 value of 0.042 μM, indicating its strong binding affinity to the S1P1 receptor. Notably, its interaction with the S1P3 receptor is minimal, as evidenced by an EC50 value of 3.47 μM. TC-SP 14 demonstrates significant pharmacological effects, including a marked reduction in blood lymphocyte counts and the attenuation of delayed type hypersensitivity response to antigen challenge [1].

Smiles

FC1=C(C2=NC=3C(S2)=CC=C(CC4=C(F)C=CC=C4)C3)C=CC(CN5CC(C(O)=O)C5)=C1

Molecular Formula

C25H20F2N2O2S

Molecular Weight

450.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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