TC-SP 14
Product Specifications
CAS Number
1257093-40-5
Target
Others|||LPL Receptor
Related Pathways
GPCR/G Protein|||Others
Bioactivity
TC-SP 14, also known as compound 14, is a highly active and potent S1P1 agonist with oral bioavailability. It exhibits an EC50 value of 0.042 ?M, indicating its strong binding affinity to the S1P1 receptor. Notably, its interaction with the S1P3 receptor is minimal, as evidenced by an EC50 value of 3.47 ?M. TC-SP 14 demonstrates significant pharmacological effects, including a marked reduction in blood lymphocyte counts and the attenuation of delayed type hypersensitivity response to antigen challenge [1].
Smiles
FC1=C(C2=NC=3C(S2)=CC=C(CC4=C(F)C=CC=C4)C3)C=CC(CN5CC(C(O)=O)C5)=C1
Molecular Formula
C25H20F2N2O2S
Molecular Weight
450.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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