MI-192
Product Specifications
CAS Number
1415340-63-4
Target
Others, Apoptosis, HDAC
Related Pathways
Apoptosis, Chromatin/Epigenetic, Others, DNA Damage/DNA Repair
Bioactivity
MI-192 is a selective HDAC2 and HDAC3 inhibitor with IC50 values of 30 nM and 16 nM, respectively. It exhibits greater selectivity for HDAC2/3 over other HDAC isomers and induces apoptosis in myeloid leukemic cells, indicating potential therapeutic use in leukemia and as an anti-stroke agent [1] [2].
Smiles
O=C1C=2C(C(=C)CN1CC3=CC=C(C(NC4=C(N)C=CC=C4)=O)C=C3)=CC=CC2
Molecular Formula
C24H21N3O2
Molecular Weight
383.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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