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CID 2745687

Product Specifications

CAS Number

264233-05-8

Target

GPCR

Related Pathways

Endocrinology/Hormones|||GPCR/G Protein

Purity

0.9911

Bioactivity

CID 2745687 is a moderately potent, concentration-dependent antagonist at human GPR35 with pIC50 = 6.70. CID 2745687 cannot effectively antagonize the agonist effects of either Zaprinast or Cromolyn disodium at rodent ortholog of GPR35 in vitro[1]. However, CID 2745687 can reverse lodoxamide-mediated anti-fibrotic effects in mice in vivo[2].

Smiles

COC(=O)c1cnn(c1C=NNC(=S)NC(C)(C)C)-c1ccc(F)cc1F

Molecular Formula

C17H19F2N5O2S

Molecular Weight

395.43

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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