CCT018159
Product Specifications
CAS Number
171009-07-7
Target
Apoptosis, HSP
Related Pathways
Metabolism, Apoptosis, Cytoskeletal Signaling
Purity
0.9979
Bioactivity
CCT018159 is a 3,4-diarylpyrazole resorcinol, an ATP-competitive HSP90ATPase inhibitor that inhibits human Hsp90β and yeast Hsp90 with IC50s of 3.2 and 6.6 μM, respectively.CCT018159 inhibits key endothelial and tumor cell functions associated with invasion and angiogenesis. CCT018159 caused cellular inhibition associated with G1 phase block and induced apoptosis.
Smiles
CC1=C(C(=NN1)C2=CC(CC)=C(O)C=C2O)C=3C=C4C(=CC3)OCCO4
Molecular Formula
C20H20N2O4
Molecular Weight
352.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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