C-021
Product Specifications
CAS Number
864289-85-0
Target
CCR
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Microbiology/Virology
Purity
>99.99%
Bioactivity
C 021 dihydrochloride is a potent CCR4 antagonist. C-021 (4-Quinazolinamine, 2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-) dihydrochloride potently inhibits functional chemotaxis in humans and mice with IC50s of 140 nM and 39 nM, respectively. It effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor (IC50: 18 nM) .
Smiles
N(C=1C2=C(N=C(N1)N3CCC(CC3)N4CCCCC4)C=C(OC)C(OC)=C2)C5CCCCCC5
Molecular Formula
C27H41N5O2
Molecular Weight
467.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS9428566-01 96 Tests
Human LETM1 domain-containing protein 1 ELISA Kit
Sign In for Pricing
View Details 
MBS9428566-02 5x 96 Tests
Human LETM1 domain-containing protein 1 ELISA Kit
Sign In for Pricing
View Details GTR15127252 1 Vial
Lentiviral mouse Vmn1r70 shRNA (UAS) - Lentiviral mouse Vmn1r70 shRNA (UAS, iRFP) plasmid
Sign In for Pricing
View Details MBS2081082-01 0.1 mL
APC-Linked Polyclonal Antibody to DNA Damage Inducible Transcript 3 (DDIT3)
Sign In for Pricing
View Details