AEG 3482
Product Specifications
CAS Number
63735-71-7
Target
JNK, Apoptosis
Related Pathways
Apoptosis, MAPK
Purity
>99.99%
Bioactivity
AEG 3482 is a potent antiapoptotic compound. AEG 3482 inhibits Jun kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70) . AEG 3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25.
Smiles
NS(=O)(=O)c1nn2cc(nc2s1)-c1ccccc1
Molecular Formula
C10H8N4O2S2
Molecular Weight
280.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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