2-Fluoropalmitic acid

Product Specifications

CAS Number

16518-94-8

Target

MMP|||Integrin|||ERK|||Acyltransferase

Related Pathways

Cytoskeletal Signaling|||Proteases/Proteasome|||MAPK|||Metabolism

Bioactivity

2-Fluoropalmitic acid (2-Fluorohexadecanoic acid), a fatty acid containing fluorine atoms, serves as a potential therapeutic agent for glioblastoma (GBM) by inhibiting the viability, proliferation, and stem-like phenotype of glioma stem cells (GSCs), suppressing the expression of phosphorylated erk, CD133, and SOX-2, and leading to decreased MMP-2 activity and increased methylation of the MGMT promoter.