ZJ 43
Product Specifications
CAS Number
723331-20-2
Target
GluR, Aminopeptidase
Related Pathways
Neuroscience, Metabolism
Bioactivity
ZJ43 is a potent inhibitor of glutamate carboxypeptidase II (K (i) = 0.8 nM) and III (K (i) = 23 nM) that inhibits the hydrolysis of NAAG (IC50 = 2.4 nM) . ZJ43 sufficiently activates group II mGluR and reduces some of the behavioral effects of PCP. ZJ43 shows an analgesic effect in neuropathic and inflammatory and pain models [1].
Smiles
CC(C)C[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=[O]CC(C)C[C@H](NC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O)C(O)=O
Molecular Formula
C24H39N4O14
Molecular Weight
607.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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