UCM05
Product Specifications
CAS Number
1094451-90-7
Target
Fatty Acid Synthase, Antibacterial, Antibiotic
Related Pathways
Microbiology/Virology, Metabolism
Purity
0.9925
Bioactivity
UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) with efficacy against HER2+ breast cancer xenografts, including cell lines resistant to anti-HER2 drugs [1]. Additionally, it functions as an inhibitor of the Filamentous temperature-sensitive protein Z (FtsZ), selectively inhibiting the growth of the Gram-positive bacterium B. subtilis with minimum inhibitory concentration (MIC) values of 100 μM, while showing no activity against the Gram-negative bacterium E. coli [2].
Smiles
Oc1cc(cc(O)c1O)C(=O)Oc1cc(OC(=O)c2cc(O)c(O)c(O)c2)c2ccccc2c1
Molecular Formula
C24H16O10
Molecular Weight
464.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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