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UCM05

Product Specifications

CAS Number

1094451-90-7

Target

Fatty Acid Synthase, Antibacterial, Antibiotic

Related Pathways

Microbiology/Virology, Metabolism

Purity

0.9925

Bioactivity

UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) with efficacy against HER2+ breast cancer xenografts, including cell lines resistant to anti-HER2 drugs [1]. Additionally, it functions as an inhibitor of the Filamentous temperature-sensitive protein Z (FtsZ), selectively inhibiting the growth of the Gram-positive bacterium B. subtilis with minimum inhibitory concentration (MIC) values of 100 μM, while showing no activity against the Gram-negative bacterium E. coli [2].

Smiles

Oc1cc(cc(O)c1O)C(=O)Oc1cc(OC(=O)c2cc(O)c(O)c(O)c2)c2ccccc2c1

Molecular Formula

C24H16O10

Molecular Weight

464.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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