What is the catalog number for CRT5?

The catalog number for CRT5 is T21795.

What sizes are available for CRT5?

CRT5 is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg.

How many pack sizes does CRT5 come in?

CRT5 is available in 4 different pack sizes.

CRT5 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CRT5?

CRT5 is manufactured by Molfinity.

What is the estimated delivery time for CRT5?

Estimated delivery time for CRT5 is approximately 10 business day(s), depending on your location.

CRT5

Product Specifications

CAS Number

1034297-58-9

Target

Others, Serine/threonin kinase

Related Pathways

Metabolism, Cell Cycle/Checkpoint, Others

Bioactivity

CRT5, a pyrazine benzamide, is a potent and selective PKD inhibitor. It inhibits VEGF-induced phosphorylation of three PKD substrates (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively), histone deacetylase 5, CREB (cAMP-response-element-binding protein), and HSP27 (heat-shock protein 27) at Ser82. Additionally, CRT5 decreases VEGF-induced endothelial migration, proliferation, and tubulogenesis[1].