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VU0359595

Product Specifications

CAS Number

1246303-14-9

Target

Antifungal, Phospholipase

Related Pathways

Metabolism, Microbiology/Virology

Purity

0.9979

Bioactivity

VU0359595 (ML-270) is a potent and selective pharmacological phospholipase D1 (PLD1) inhibitor with an IC50 of 3.7 nM. VU0359595 is >1700-fold selective for PLD1 over PLD2 (IC50 of 6.4 μM) . VU0359595 can be used for the research of cancer, diabetes, neurodegenerative and inflammatory diseases.

Smiles

C[C@@H](CN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O)NC(=O)[C@@H]1C[C@H]1c1ccccc1

Molecular Formula

C25H29BrN4O2

Molecular Weight

497.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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