4-iodo-SAHA
Product Specifications
CAS Number
1219807-87-0
Target
Others, HDAC
Related Pathways
Chromatin/Epigenetic, Others, DNA Damage/DNA Repair
Bioactivity
4-Iodo-SAHA (1k), an orally active inhibitor of both class I and class II histone deacetylase (HDAC), exhibits EC50 values of 1.1, 0.95, 0.12, 0.24, 0.85, and 1.3 μM for Skbr3, HT29, U937, JA16, and HL60 cell lines, respectively. This compound holds potential for cancer research purposes [1].
Smiles
N(C(CCCCCCC(NO)=O)=O)C1=CC=C(I)C=C1
Molecular Formula
C14H19IN2O3
Molecular Weight
390.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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