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4-iodo-SAHA

Product Specifications

CAS Number

1219807-87-0

Target

Others|||HDAC

Related Pathways

Chromatin/Epigenetic|||Others|||DNA Damage/DNA Repair

Bioactivity

4-Iodo-SAHA (1k), an orally active inhibitor of both class I and class II histone deacetylase (HDAC), exhibits EC50 values of 1.1, 0.95, 0.12, 0.24, 0.85, and 1.3 ?M for Skbr3, HT29, U937, JA16, and HL60 cell lines, respectively. This compound holds potential for cancer research purposes [1].

Smiles

N(C(CCCCCCC(NO)=O)=O)C1=CC=C(I)C=C1

Molecular Formula

C14H19IN2O3

Molecular Weight

390.22

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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