PF-9184
Product Specifications
CAS Number
1221971-47-6
Target
Prostaglandin Receptor, PGE Synthase
Related Pathways
Immunology/Inflammation, GPCR/G Protein
Purity
0.9764
Bioactivity
PF-9184 is a potent and selective inhibitor of human microsomal prostaglandin E synthase-1 (mPGES-1) with an IC50 of 16.5 nM, and it inhibits IL-1β-induced PGE2 synthesis in vitro.
Smiles
OC1=C(NS(=O)(=O)c2ccccc12)C(=O)Nc1ccc(cc1)-c1ccc(Cl)c(Cl)c1
Molecular Formula
C21H14Cl2N2O4S
Molecular Weight
461.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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