PF-9184

Product Specifications

CAS Number

1221971-47-6

Target

Prostaglandin Receptor|||PGE Synthase

Related Pathways

Immunology/Inflammation|||GPCR/G Protein

Purity

0.9764

Bioactivity

PF-9184 is a potent and selective inhibitor of human microsomal prostaglandin E synthase-1 (mPGES-1) with an IC50 of 16.5 nM, and it inhibits IL-1?-induced PGE2 synthesis in vitro.

Smiles

OC1=C(NS(=O)(=O)c2ccccc12)C(=O)Nc1ccc(cc1)-c1ccc(Cl)c(Cl)c1

Molecular Formula

C21H14Cl2N2O4S

Molecular Weight

461.32

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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