GP-82996
Product Specifications
CAS Number
359886-84-3
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
0.9994
Bioactivity
GP-82996 (CINK4) is a pharmacological inhibitor specifically targeting CDK4/6, exhibiting IC50 values of 1.5 μM for CDK4/cyclin D1, 5.6 μM for CDK6/cyclin D1, and 25 μM for Cdk5/p35. It effectively induces apoptosis in U2OS cancer cells, positioning it as a potential investigational tool in cancer research [1] [2].
Smiles
C(N1C=2C(=CC(NC=3N=C(N[C@@H]4CC[C@@H](O)CC4)C=C(NCC)N3)=CC2)C=C1)C5=CC=CC=C5
Molecular Formula
C27H32N6O
Molecular Weight
456.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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