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8-CPT-Cyclic AMP (sodium salt)

Product Specifications

CAS Number

93882-12-3

Target

PDE|||PKA|||Others

Related Pathways

Others|||Tyrosine Kinase/Adaptors|||Metabolism

Bioactivity

8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA) and a potent inhibitor of cyclic GMP-specific phosphodiesterase (PDE VA) with an inhibitory concentration (IC50) of 0.9 ?M. It also inhibits PDE III and PDE IV while significantly activating Epac, demonstrating diverse pharmacological activities [1] [2].

Smiles

NC1=C2C(N([C@@H]3O[C@@]4([H])[C@](OP([O-])(OC4)=O)([H])[C@H]3O)C(SC5=CC=C(C=C5)Cl)=N2)=NC=N1.[Na+]

Molecular Formula

C16H14ClN5NaO6PS

Molecular Weight

493.79

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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