8-CPT-Cyclic AMP (sodium salt)
Product Specifications
CAS Number
93882-12-3
Target
PDE|||PKA|||Others
Related Pathways
Others|||Tyrosine Kinase/Adaptors|||Metabolism
Bioactivity
8-CPT-Cyclic AMP (8-CPT-cAMP) sodium is a selective activator of cyclic AMP-dependent protein kinase (PKA) and a potent inhibitor of cyclic GMP-specific phosphodiesterase (PDE VA) with an inhibitory concentration (IC50) of 0.9 ?M. It also inhibits PDE III and PDE IV while significantly activating Epac, demonstrating diverse pharmacological activities [1] [2].
Smiles
NC1=C2C(N([C@@H]3O[C@@]4([H])[C@](OP([O-])(OC4)=O)([H])[C@H]3O)C(SC5=CC=C(C=C5)Cl)=N2)=NC=N1.[Na+]
Molecular Formula
C16H14ClN5NaO6PS
Molecular Weight
493.79
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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