Sp-Cyclic AMPS (sodium salt)
Product Specifications
CAS Number
142439-95-0
Target
Others|||PKA|||PDE
Related Pathways
Metabolism|||Tyrosine Kinase/Adaptors|||Others
Bioactivity
Sp-cAMPS sodium salt is an analog of cAMP that serves as a potent activator of cAMP-dependent PKA I and PKA II, and as a competitive phosphodiesterase (PDE3A) inhibitor with a Ki of 47.6 ?M. It also binds the PDE10 GAF domain with an EC50 of 40 ?M [1] [2] [3].
Smiles
O[C@H]1[C@@H](O[C@@]2([H])[C@@]1([H])OP([S-])(OC2)=O)N3C4=NC=NC(N)=C4N=C3.[Na+]
Molecular Formula
C10H12N5NaO5PS+
Molecular Weight
367.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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