NVP DPP 728 dihydrochloride
Product Specifications
CAS Number
247016-69-9
Target
Others, Proteasome
Related Pathways
Ubiquitination, Proteases/Proteasome, Others
Bioactivity
NVP-DPP728 is a potent, reversible, nitrile-dependent inhibitor of dipeptidyl peptidase IV (DPP-IV) with an inhibition constant (K i) of 11 nM for human DPP-IV amidolytic activity. By inhibiting the degradation of glucagon-like peptide-1 (GLP-1), NVP-DPP728 enhances insulin release following glucose intake, making it useful for diabetes research [1].
Smiles
C(CNCCNC1=CC=C(C#N)C=N1)(=O)N2[C@H](C#N)CCC2
Molecular Formula
C15H18N6O
Molecular Weight
298.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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